Human Anatomy

Nervous System

Nerves and specialized cells called neurons transmit electrical and chemical signals between different parts of the body to control bodily functions.

How the Nervous System Is Organized

The nervous system senses and processes stimuli from the environment and body and responds appropriately. It provides fast, coordinated responses through interconnected cells. These cells are called neurons (nerve cells) and glia (glial cells).

Neurons are the functional units of the nervous system. The human brain contains approximately 86 billion neurons. Glia support neurons, both structurally and metabolically. Glia outnumber neurons.

Neurons generate electrical signals, called action potentials, that allow information to be quickly transmitted throughout the body. Neurons transmit this this information along thin fibers, which causes chemicals (called neurotransmitters) to be released at junctions (or synapses).

A cell that receives a signal may be excited, inhibited, or modulated in other ways. The connections between neurons form neural pathways that create larger networks that affect an individual’s perceptions and responses to stimuli. The nervous system can be broadly separated into two categories: central and peripheral. The central nervous system (CNS) consists of the brain and spinal cord. The brain receives and processes sensory information, initiates responses, stores memories, and gratis thoughts and emotions. The spinal cord conducts these signals to and from the brain and controls reflexes.

The peripheral nervous system (PNS) consists of nerves and ganglia, which are masses of tissue that contain neuron cell bodies. The PNS is the part of the nervous system found outside of the CNS. It is made up of sensory neurons and motor neurons. Sensory neurons sense information from the body and send data to the CNS for processing. Motor neurons send data to the CNS to muscles and glands, which respond accordingly. Motor neurons are divided between two systems: the somatic (or voluntary) nervous system and the automatic nervous system.

The somatic nervous system controls intentional movements. The autonomic nervous system controls involuntary responses; it is divided into the sympathetic nervous system and the parasympathetic nervous system. The sympathetic division is responsible for rapid fight-or-flight responses to stimuli. It is activated during high-stress times. The parasympathetic division manages rest-and-digest responses to low-stress stimuli.

Brain: The body’s command center and one of the largest and most complex organs. It is made up of more than 100 billion nerves that communicate with trillions of synapses (connections)

Brain stem: Composed of the midbrain, pons, and medulla oblongata, this organ controls the flow of messages between the brain and the rest of the body, including key functions like breathing and heart rate

Vagus nerve: The longest and most complex cranial nerve, which runs through the face and thorax to the abdomen. They oversee a range of critical bodily functions, including digestion, heart rate, and speech.

Brachial plexus: This group of nerves travels from the spinal cord in the neck down the arms; they control the muscles of the shoulders, elbows, wrists, and hands and provide feeling to the limbs

Spinal cord: This long, thin tube lies within protective vertebrae. Extending from the medulla oblongata in the brain stem to the lumbar region, it transmits signals from the motor cortex to the rest of the body and coordinates reflexes

Intercostal nerve: These somatic nerves rise from the anterior divisions of the thoracic nerves in the spine. They control muscle contractions and provide sensory information, including information related to touch from the skin

Iliohypogastric nerve: These nerves supply sensations to the skin in the lateral gluteal and hypogastric regions; they also supply motor signals to the internal oblique and transverse abdominal muscles

Lumbar plexus: This web of autonomic, motor, and sensory nerves is embedded in the poses major muscle, where it passes in front of the hip joint. Along with the sacral plexus, it innervates the lower extremities, glutei, and groin.

Median nerve: This main nerve is found in the front of the forearm and controls muscle movement in the forearm and thenar eminence (the ball of the thumb). This nerve controls coarse hand movements, so it is often called the “laborer’s nerve”

Ulnar nerve: Traveling from the shoulder to the wrist, this nerve is chiefly responsible for hand movements by providing nerve function

Pudendal nerve: This main nerve of the perineum carries sensation from the external genitalia and the skin around the anus and perineum. It also provides motor function to certain pelvic muscles

Sciatic nerve: Traveling down the back of the leg from the lower spine, the body’s largest nerve is formed by five nerve roots. It supplies sensation to the lower legs and the skin of the feet

Common perineal nerve: This is the smaller terminal branch of the sciatic nerve, it innervates the short head of the biceps muscle

Tibial nerve: This branch of the sciatic nerve rises from the popliteal space and follows the course of the tibial artery: it innervates the muscles of the lower legs and feet

Deep perineal nerve: It innervates the front section of the extensor muscles in the legs. It rises from the lateral side of the front of the legs, between the peroneus longs muscle and the neck of the fibula

Superficial peroneal nerve: These nerves, at the terminus of the common perineal nerve, supply the perineal longs and perineal braves, which form the lateral compartment of the lower legs. They help evert (turn out) the feet and thus act at the subtler joint (at the back of the feet)

The Nervous System

Nerves and cells

Neurons and glia communicate with other cells via synapses, which are junctions along which both electrical and chemical signals can be quickly transmitted. Neurons transmit signals between each other and from one part of the body to the other, while glia regulate homeostasis, which protects and supports neurons.

Neurons (also called nerve cells) have a cell body )or some), which is where the nucleus is found. Most of a neuron’s proteins are produced in the soma. Both dendrites, which are short branching processes, and long axons extend from the soma. The dendrites receive and process information. Incoming signals can be excitatory, meaning they keep the neuron fire in order to create an impulse, or inhibitory, meaning they make the neuron from firing in order to prevent an action. A neuron may have multiple dendrites and receive thousands of input signals. The sum of all excitatory and inhibitory signals determines whether a neuron will fire. If the neuron fires, a nerve impulse, called an action potential, is sent down the axon.

Axons move information away from the cell body at the axon hillock. Axons are coated in myelin (called a myelin sheath), which helps insulate them and quickly conduct nerve impulses. Axons split into many branches and feature swellings known as axon terminals ( or nerve terminals). These terminals connect with target cells to transmit information.

Glial cells are important supporting cells to neurons and outnumber them 10 to 1. They help neurons expand in the proper direction, buffer ions and chemicals that would harm neurons, and create myelin sheaths around axons. They also respond to nerve activity and modulate communication between neurons.

There are many types of Lia. The glia in the central nervous system (CNS) include oligodendrocytes, astrocytes, ependymal cells, and microglial cells. Oligodendrocytes form the myelin sheaths around axons. Astrocytes provide nutrients to neurons, maintain their extracellular environment, and provide structural support to neurons. Ependymal cells make cerebrospinal fluid, which cushions neurons. Microglial cells remove toxins and dead cells, and they also form the myelin sheaths as well as the satellite cells that help structure neurons and provide nutrients to them.

Neurons communicate within themselves through electrical signals, and they generally communicate with other cells via electrical signals that are converted into chemical signals.

Myelin is composed of two types of support cells. In the CNS, oligodendrocytes wrap around axons to create the myelin sheath. Astrocytes are star-shaped support cells found in the brain and spinal cord and are the most abundant Dial cells in the CNS. In the PNS, Schwann cells produce myelin.

Myelin is the whitish sheath found around many nerve fibers. It isa mixture of proteins and phospholipids that speeds impulses.

Astrocytes, also known as astroglia, are glial cells found in the brain that connect neurons to blood vessels.

Microglial cells remove toxins and dead cells. Schwann cells form the myelin sheaths around axons in the PNS and provide nutrients and structure to those neurons.

Neurons

There are many types of neurons. They can be classified by function (sensory, motor, or interneuron) or shape (unipolar, bipolar, multipolar, or pseudounipolar). Neurons are electronically excitable cells that allow the brain to communicate with the rest of the body. These fundamental units of the brain and nervous system send and receive signals; a neuron’s structure determines how it transmits messages.

In the human body, information is passed through synapses via chemical messengers called neurotransmitters. An action potential (a nerve impulse) moves down an axon toward its terminal, releasing neurotransmitters from the presynaptic neuron. These neurotransmitters then cross the synapse and bind to membrane receptors on postsynaptic neurons, creating an excitatory or inhibitory signal. Just as neurons can receive multiple signals through their dendrites, they can also send multiple signals through their axon terminals.

There are four basic shapes: unipolar, bipolar, multipolar, and pseudounipolar. Unipolar neurons have one structure that extends away from their soma. They are not fond in vertebrates, such as humans, but are seen in insects.

Bipolar neurons have one axon and one dendrite that extends from the soma. The retinal cells of the eyes are bipolar. They receive signals from photoreceptor cells that identify light and transmit these signals to the brain for interpretation.

Multipolar neurons are the most common type. They have on axon and multiple